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Onsat 8 mg En Vente Europe
#11
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#12
On pense que le modafinil agit via un certain nombre de récepteurs de la dopamine, principalement les récepteurs DRD1 et DRD2 de type D1. Le modafinil appartient à un groupe de médicaments appelés stimulants du SNC. Cette suggestion est basée sur les découvertes de son utilisation dans des contextes thérapeutiques pour améliorer la somnolence causée par la narcolepsie, les troubles du sommeil liés au travail posté et l'apnée obstructive du sommeil. Il n'a aucun des effets psychotomimétiques ou autres effets nocifs des amphétamines. Le modafinil est administré par voie orale et est rapidement absorbé dans la circulation sanguine. Il s'agit d'un stimulant du système nerveux qui a été utilisé hors AMM comme prétendu activateur cognitif pour améliorer l'éveil dans des études animales et humaines, mais les preuves de son efficacité en tant qu'activateur cognitif restent anecdotiques. Il existe des rapports contradictoires quant aux effets de l'utilisation chronique de caféine et de modafinil. Le modafinil peut également avoir des effets additifs avec d'autres stimulants du SNC tels que l'amphétamine et le méthylphénidate. Le modafinil est généralement considéré comme sûr pour une utilisation continue. Il a toujours une activité d'agoniste partiel sur le récepteur GABAA, avec une CE50 d'environ 4 mg/L. Il est pris une ou deux fois par jour. Il a été démontré que le modafinil améliore la mémoire de travail et la capacité d'attention, en particulier dans les tâches impliquant des compétences telles que la mémoire et l'apprentissage. Les symptômes narcoleptiques peuvent être chroniques ou épisodiques. C'est un composé cristallin blanc à légèrement jaune-blanc, qui est légèrement soluble dans l'eau. Bien que la CPAP soit le traitement le plus courant de l'apnée du sommeil, elle n'est pas efficace pour tous les patients et l'observance peut être un problème. modafinil vente Le modafinil a été développé par le neuroscientifique français Michel Jouvet dans les années 1970, spécifiquement pour les personnes souffrant de somnolence diurne excessive (EDS) associée à la narcolepsie. En raison de cette propriété, il peut provoquer des maux de tête et des troubles du sommeil. C'est un composé cristallin blanc à légèrement jaune-blanc, qui est légèrement soluble dans l'eau. Le modafinil semble affecter le cycle de sommeil du cerveau, augmentant l'éveil et l'attention. Le modafinil est un stimulant du SNC dérivé de l'amphétamine qui modifie la neurotransmission, activant généralement principalement la noradrénaline (norépinéphrine) et la dopamine, mais également l'acétate d'indole-5-yle à des doses plus élevées. Les effets pharmacologiques du modafinil ont été étudiés chez l'animal et chez l'homme. Chez les adultes en bonne santé qui ne subissent normalement pas de telles augmentations, le modafinil entraîne une augmentation dose-dépendante des périodes d'éveil, améliore la vigilance et réduit la fatigue et la somnolence. Le modafinil est disponible aux États-Unis, au Canada et au Royaume-Uni. Les personnes privées de sommeil rapportent qu'elles se concentrent plus facilement en classe et ressentent moins de fatigue le matin. Le modafinil peut également causer des problèmes chez les enfants et son utilisation n'est pas recommandée pendant la grossesse.

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#13
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